Postvaccinal parkinsonism
Identifieur interne : 005F41 ( Main/Exploration ); précédent : 005F40; suivant : 005F42Postvaccinal parkinsonism
Auteurs : Alves [Brésil] ; Egberto R. Barbosa [Brésil] ; Milberto Scaff [Brésil]Source :
- Movement Disorders [ 0885-3185 ] ; 1992.
English descriptors
- KwdEn :
- Bromocriptine (administration & dosage), Child, Preschool, Dose-Response Relationship, Drug, Encephalitis, Encephalomyelitis, Acute Disseminated (diagnosis), Encephalomyelitis, Acute Disseminated (drug therapy), Humans, Levodopa (administration & dosage), Magnetic Resonance Imaging, Male, Measles Vaccine (administration & dosage), Measles Vaccine (adverse effects), Neurologic Examination (drug effects), Parkinson Disease, Postencephalitic (diagnosis), Parkinson Disease, Postencephalitic (drug therapy), Parkinsonism, Rigid‐akinetic syndrome, Substantia Nigra (pathology).
- MESH :
- chemical , administration & dosage : Bromocriptine, Levodopa, Measles Vaccine.
- chemical , adverse effects : Measles Vaccine.
- diagnosis : Encephalomyelitis, Acute Disseminated, Parkinson Disease, Postencephalitic.
- drug effects : Neurologic Examination.
- drug therapy : Encephalomyelitis, Acute Disseminated, Parkinson Disease, Postencephalitic.
- pathology : Substantia Nigra.
- Child, Preschool, Dose-Response Relationship, Drug, Humans, Magnetic Resonance Imaging, Male.
Abstract
A 5‐year‐old boy, with a history of fever beginning 15 days after a vaccination for measles, developed a rigid‐akinetic syndrome 3 days after the fever began. A spinal tap obtained 1 week after the onset of fever showed pleocytosis with a monocellular pattern. A CT scan of the head and EEG did not disclose any abnormality. An MRI performed 3 months after the event, however, showed clear‐cut evidence of bilateral substantia nigra lesions, suggesting secondary gliosis. The response to levodopa was good, but adverse reactions appeared early. The child is now 7 years old. Bromocriptine, deprenyl, and levodopa have produced a remarkable improvement of the parkinsonian features.
Url:
DOI: 10.1002/mds.870070213
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1992">1992</date><biblScope unit="vol">7</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="178">178</biblScope><biblScope unit="page" to="180">180</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">C63AAA6CD2DA3DF7E9FBFD7A69E7B3C9A1A488E1</idno><idno type="DOI">10.1002/mds.870070213</idno><idno type="ArticleID">MDS870070213</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bromocriptine (administration & dosage)</term><term>Child, Preschool</term><term>Dose-Response Relationship, Drug</term><term>Encephalitis</term><term>Encephalomyelitis, Acute Disseminated (diagnosis)</term><term>Encephalomyelitis, Acute Disseminated (drug therapy)</term><term>Humans</term><term>Levodopa (administration & dosage)</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Measles Vaccine (administration & dosage)</term><term>Measles Vaccine (adverse effects)</term><term>Neurologic Examination (drug effects)</term><term>Parkinson Disease, Postencephalitic (diagnosis)</term><term>Parkinson Disease, Postencephalitic (drug therapy)</term><term>Parkinsonism</term><term>Rigid‐akinetic syndrome</term><term>Substantia Nigra (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Bromocriptine</term><term>Levodopa</term><term>Measles Vaccine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Measles Vaccine</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Encephalomyelitis, Acute Disseminated</term><term>Parkinson Disease, Postencephalitic</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Neurologic Examination</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Encephalomyelitis, Acute Disseminated</term><term>Parkinson Disease, Postencephalitic</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Substantia Nigra</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term><term>Dose-Response Relationship, Drug</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 5‐year‐old boy, with a history of fever beginning 15 days after a vaccination for measles, developed a rigid‐akinetic syndrome 3 days after the fever began. A spinal tap obtained 1 week after the onset of fever showed pleocytosis with a monocellular pattern. A CT scan of the head and EEG did not disclose any abnormality. An MRI performed 3 months after the event, however, showed clear‐cut evidence of bilateral substantia nigra lesions, suggesting secondary gliosis. The response to levodopa was good, but adverse reactions appeared early. The child is now 7 years old. Bromocriptine, deprenyl, and levodopa have produced a remarkable improvement of the parkinsonian features.</div></front></TEI><affiliations><list><country><li>Brésil</li></country></list><tree><country name="Brésil"><noRegion><name sortKey="Alves" sort="Alves" uniqKey="Alves" last="Alves">Alves</name></noRegion><name sortKey="Barbosa, Egberto R" sort="Barbosa, Egberto R" uniqKey="Barbosa E" first="Egberto R." last="Barbosa">Egberto R. Barbosa</name><name sortKey="Scaff, Milberto" sort="Scaff, Milberto" uniqKey="Scaff M" first="Milberto" last="Scaff">Milberto Scaff</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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